Neuroscience· 2 min read

What is the Salience Network?

Why does depression make you feel so disconnected? The answer lies in the Salience Network, your attention’s traffic director, which in depression loses flexibility and gets stuck activating the Default Mode Network.

Why does depression make you feel so disconnected? The answer lies in your "Salience Network".

Your attention’s traffic director

Tracing a neural bridge from the anterior insula to the cingulate cortex, this network is your attention’s traffic director. It constantly decides whether you should focus on the outside world or explore your own thoughts.

Normally, it shifts focus effortlessly.

What happens in depression

But in depression, this switch breaks down. The network loses flexibility and gets stuck activating your Default Mode Network.

That is why you become trapped in a loop of rumination and self-criticism, blind to what is happening around you.

How Transcranial Magnetic Stimulation helps

This is where neuroscience comes in. Transcranial Magnetic Stimulation (or TMS) sends strategic magnetic pulses to "reset" the system.

It repairs this bridge and strengthens the connections so you can switch off the mental noise, return to the present and never feel disconnected again.

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